Validating the assessment of glucose 6 phosphate dehydrogenase g6pd dating site for professional
We evaluated a new point-of-care G6PD screening kit (Care Start G6PD, CSG) against FST using graded Cu Cl treatments to simulate variable hemizygous states, and varying proportions of Cu Cl-treated RBC suspensions to simulate variable heterozygous states of G6PD deficiency.
In experiments double-blinded to Cu Cl treatment, technicians reading FST and CSG test (n = 269) classified results as positive or negative for deficiency.
At G6PD activity ≤40% of normal (n = 112), CSG test was not inferior to FST in detecting G6PD deficiency (P = 0.003), with 96% vs 90% (P = 0.19) sensitivity and 75% and 87% (P = 0.01) specificity, respectively.
to place dormant forms in the liver called hypnozoites.
These parasites typically cause 3 or more clinical attacks in relatively quick succession in the months after the primary attack, or may do so up to 1 or 2 years later.